Thursday, August 16, 2007

Thursday August 16, 2007
Keppra (Levetiracetam) and renal failure


Keppra (Levetiracetam), an anti-epileptic drug is now available in IV form and is frequently used in ICU. Its important to remember that Keppra metabolized through kidney and dose needs to be reduced in renal insufficiency by 50%. Also keppra is dialyzable and ideally should be given after dialysis on dialysis day.

Unfortunately, there is no test available to measure therapeutic blood levels.