Friday, August 31, 2007

Friday August 31, 2007
Cefepime in CVVHD


Q; Do you need to adjust Cefepime in CVVHD. Yes OR No ?

A: No

Cefepime is dialysable. In patients on CVVHD (Continuous venovenous haemodiafiltration), no dosage adjustment for cefepime is required and the dosage regime as with normal renal function should be administered.In patients on HD (hemodialysis), dose of 1 gram every 24 hours is recommended. A supplemental dose of cefepime is advisable at the end of a HD session due to the fact that cefepime is dialysable.

Related previous pearl: Vancomycin dosing in CRRT